DNA Polymerase Kappa Research Products: Novus Biologicals
DNA polymerases and cancer | Nature Reviews Cancer
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
NF-κB Signaling | NF-kappaB Pathway
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
DNA Polymerase Kappa Antibody (6F2) (H00051426-M01): Novus Biologicals
DNA polymerase eta: A potential pharmacological target for cancer therapy - Saha - 2021 - Journal of Cellular Physiology - Wiley Online Library
Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender - ScienceDirect
DNA polymerase ι is acetylated in response to SN2 alkylating agents | Scientific Reports
Inhibition of host NF-kappa-B by virus ~ ViralZone
DNA polymerase κ: Friend or foe? | Science Signaling
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1 - Journal of Biological Chemistry
Inhibition of mutagenic translesion synthesis: A possible strategy for improving chemotherapy? | PLOS Genetics
DNA Polymerase Kappa Research Products: Novus Biologicals
NF-κB inhibitors in treatment and prevention of lung cancer - ScienceDirect
RCSB PDB - 6BS1: Crystal Structure of Human DNA polymerase kappa in complex with DNA containing the major cisplatin lesion
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
