Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance | Cell Death & Disease
Dysregulation of BCL-2 family proteins by leukemia fusion genes - ScienceDirect
Targeting BCL-2 regulated apoptosis in cancer | Open Biology
Targeting BCL-2 regulated apoptosis in cancer | Open Biology
BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis | PLOS Pathogens
Basal Patologi KU - BAD, BID and PUMA proteins shift the balance between the pro-apoptotic and anti-apoptotic family members by neutralizing the actions of anti-apoptotic proteins like BCL2 and BCL-XL, thereby promoting
Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance - ScienceDirect
A) Bcl-2 family member effector proteins (Bax and Bak) oligomerize and... | Download Scientific Diagram
IJMS | Free Full-Text | Co-Operativity between MYC and BCL-2 Pro-Survival Proteins in Cancer
Frontiers | Targeting the Bcl-2 Family in B Cell Lymphoma
BH3-Only Proteins Noxa and Puma in Apoptosis Regulation | Encyclopedia MDPI
Frontiers | Targeting Bcl-2 Proteins in Acute Myeloid Leukemia
BCL‐2‐family protein tBID can act as a BAX‐like effector of apoptosis | The EMBO Journal
Unified model of BCL-2 protein family interactions. BH3-only activators... | Download Scientific Diagram
PUMA decreases the growth of prostate cancer PC-3 cells independent of p53
Why do BCL-2 inhibitors work and where should we use them in the clinic? | Cell Death & Differentiation
Interplay of Bcl-2 Proteins Decides the Life or Death Fate ~ Fulltext
Biomolecules | Free Full-Text | The Bcl-2 Family: Ancient Origins, Conserved Structures, and Divergent Mechanisms
PUMA-mediated apoptosis. PUMA is induced by a wide range of death... | Download Scientific Diagram
BCL-2
PUMA binding induces partial unfolding within BCL-xL to disrupt p53 binding and promote apoptosis | Nature Chemical Biology
Cooperation of BH3-only proteins in killing neurons
Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | PNAS
Efficacy and specificity of inhibitors of BCL-2 family protein interactions assessed by affinity measurements in live cells | Science Advances
A review of the role of Puma, Noxa and Bim in the tumorigenesis, therapy and drug resistance of chronic lymphocytic leukemia | Cancer Gene Therapy
